A new 2-ml beef friendly vaccine for the protection against the blackleg, malignant edema, black disease, clostridium sordellii infections, enterotoxaemia and enteritis caused by Lc. perfringens types C and D and bovine pneumonic pasteurellosis caused by pasteurella haemolytica Type A1. Dosate: 2-ml subcutaneously, repeat with 2 ml Ultra Choice 7 in 4 to 6 weeks, boost with 2 ml Ultrachoice 7 annually.

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> ONE SHOT ULTRA 7Clostridium Chauvoei-septicum-Novyi-Sordellii_Perfringens Types C & D pasteurella Haemolytica Bacterin-Toxoid For Vaccination of healthily cattle as an in preventing disease caused by clostridium chauvoei, CL septicum, CL Novyi, CL sordellii, Cl prefringens types C&D and pasteurella Haemolytica type A1.:

DISEASE DESCRIPTION: Pneumonic pasteurellosis caused by P. Haemolytica Type A1 has results in substantial economic losses in the cattle industry The disease condition, known as shipping fever, often prevents optimal weight gain in infected cattle and may result in death. Clinical signs may include difficult breathing, nasal discharge, reduced feed intake, fever and increased pulse rate.

DIRECTIONS: Aseptically Rehydrate the freeze-dried Bacterin-Toxoid with the accompanying vial of diluent, Shake well, and administer 2 ml subcutaneously. In accordance with beef Quality Assurance guidelines, this product should be administered subcutaneously (SC) under the skin. Healthy cattle should receive a second 2-ml dose of ultra choice 7 4-6 weeks later. Annual revaccination with a single dose of ULTRA CHOICE 7 is recommended. Revaccination with one shot Whenever subsequent stress or exposure is likely. Good animal husbandry and herd management practices should be employed. See enclosed leaflet for complete directions and precautions.

GUARANTEED ANALYSIS

PRECAUTION: Store at 2-7 C Do not freeze Use entire contents when first opened. Sterilized syringes and needles should be used to administer this vaccine. Do not vaccinate within 21 days before slaughter. Not for use in sheep. Contains formalin as preservative. Temporary local swelling at injection site may occur after use. Initial antidote of Epinephrine is recommended and should be followed with appropriate supportive therapy. This product has been shown to be efficacious in healthy animals. A protective immune response may not be elicited if animals are incubating an infectious disease, are malnourished or parasitized, are stressed de to shipment or environmental conditions, are otherwise immunocompromised, or the vaccine is not administered in accordance with label directions.

SAFTEY AND EFFICACY: In safety studies involving 595 animals, no untoward reactions were noted follow vaccination did result in small, temporary injection site swelling. Efficacy of the P Haemolytica fraction in one shot ultra 7 demonstrated in a challenge- of immunity study. Cattle (300-550lb) vaccinated with 1 dose of one shot ultra 8 were subjected to severe experimental challenge at 2 week post vaccination. With a heterologous strain of P Haemolytica type A1 four days post challenge, animals were necropsied and individual lungs were evaluated for lung damage and

QUESTIONS OR COMMENTS: Technical inquiries should be directed to Pfizer Animal Health Technical Services, (800)336-5288 (USA), (800)461-0917Canada)