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TETANUS ANTITOXIN. Equine Origin.

INDICATIONS: For the prevention and treatment of tetanus in animals. Contains phenol and thimerosal as preservatives.

DOSAGE AND ADMINISTRATION: Tetanus antitoxin confers immediate passive immunity lasting about 7 to 14 days. 1500 units administered subcutaneously or intramuscularly is the recommended dose for prevention. Large doses of Tetanus Antitoxin may provide beneficial response in animals already infected with tetanus but success of treatment is not assured. For treatment administer 10,000 to 50,000 units to horses and cattle, 3,000 to 15,000 units to sheep and swine. Animals that suffer slow healing puncture wounds or deep abrasions should be given a second dose of antitoxin in 7 days and additionally as considered necessary.

PRECAUTIONS Do not treat “meat” animals within 21 days before slaughter. Anaphylactoid reaction sometimes follows administration of products of this nature. If noted, administer adrenalin or equivalent. A condition referred to as “serum hepatitis” infrequently occurs in horses. The literature associates this partially with the injection of biologics containing equine serum or tissue. This connection is based, at the present time, upon supposition and not upon scientific evidence as efforts to experimentally reproduce such a condition in horses have not been successful. It seems prudent, however, in view of the published implication, to make users aware of it. Some of the same publications that refer to “serum hepatitis” continue to recommend the use of Tetanus Antitoxin in horses that have suffered wounds that may have been contaminated with Clostridium tetani and the immunization status is unknown. If user has any questions consult with a veterinarian.

OTHER INFORMATION: Store in dark at 2 to 7 degrees C. Use entire contents when first opened. Contains phenol and thimerosal as preservatives. Tetanus Antitoxin is available in 15,000 unit vials and in packages containing 10x1,500 unit vials.